This web page is made up of quick information regarding bortezomib and a group of backlinks to far more details about the use of this drug, study final results, and ongoing clinical trials.
Talk to your health practitioner Should you have questions about sorts of delivery Handle which will be just right for you. In the event you or your lover turn out to be pregnant whilst applying bortezomib or for seven months right after your closing dose, call your medical professional immediately.
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This medication is supplied by injection right into a vein or under the skin by a health and fitness care Qualified. When you are getting this medication beneath the pores and skin, Ensure that the injection web-site is changed each time to lessen harm underneath the skin.
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Right before working with this medication, tell your health care provider or pharmacist When you are allergic to it; or if you have another allergy symptoms. This merchandise may well incorporate inactive ingredients (which include boron, mannitol), which may cause allergic reactions or other complications. Speak to your pharmacist For additional details.
fosamprenavir will increase the amount or outcome of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
bortezomib will increase the degree or influence of midazolam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Coadministration of moderate CYP3A4 inhibitors with midazolam intranasal could bring about greater midazolam systemic exposure, which may extend sedation.
atazanavir will improve the stage or influence of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use CP-866087 Warning/Observe.
mifepristone will increase the level or influence of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
apalutamide will decrease the extent or impact of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with prescription drugs which might be CYP3A4 substrates may lead to lessen publicity to these medicines.
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Indicated for procedure of sufferers with mantle mobile lymphoma as first-line in Earlier untreated patients or whoever has relapsed